Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant.

نویسندگان

  • Akira Yoshimura
  • Chenjie Zhu
  • Kyle R Middleton
  • Anthony D Todora
  • Brent J Kastern
  • Andrey V Maskaev
  • Viktor V Zhdankin
چکیده

Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.

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عنوان ژورنال:
  • Chemical communications

دوره 49 42  شماره 

صفحات  -

تاریخ انتشار 2013